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Level Up Your Purification with Our Scalable CPC Systems

CPC is a silica-free alternative to traditional chromatography methods with comparable yields and purity. The primary difference from other techniques is that CPC uses two non-miscible liquid phases and rotors rather than a solid column, which makes it a cost-effective method with less of an impact on the environment. The stationary phase is maintained in the chromatography column by a centrifugal field created by the rotation of the rotor. The components in complex mixtures are separated based on their partition coefficient between the stationary and mobile phases.

We offer a variety of scalable CPC solutions, from lab- to process-scale production, that have been developed based on years of experience in the liquid chromatography industry.

Purification of Forsythiaside A From Forsythia Suspensa by CPC

Forsythiaside A, a phenylethanoid glycoside, is one of the major active constituents extracted from the air-dried fruits of Forsythia suspensa and has been reported to possess a wide range of pharmacological properties, including anti-inflammatory and antioxidant activities. This application note discusses a simple, fast, and cost-efficient method to prepare pure compounds using a centrifugal partition chromatography (CPC) system.



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CPC Products and Systems

CPC 1000 PRO

Our reusable, silica-free centrifugal partition chromatography (CPC) columns offer high injection capacities of milligram to multi-kilograms resulting in 95% recoveries with 99% purity or better. The CPC 1000 PRO has an injection capacity of up to 100 g and a max elution flow rate of 350 mL/min. CPC columns also use approximately five times less solvent than more traditional columns, saving you money on solvent and disposal costs.

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VERITY® CPC Lab MS System

The VERITY CPC Lab MS System allows you to perform mass-directed purification of target compounds by centrifugal partition chromatography (CPC). This automated, cost-effective, liquid-liquid purification technique utilizes reusable, silica-free chromatographic columns and the VERITY® 1920 Mass Spectrometer to streamline your workflow and allow you to quickly isolate added value molecules with high yields and purity.

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VERITY® CPC Pilot System

The VERITY CPC Pilot System combines the PLC 2500 Purification System with a VERITY CPC 1000 PRO for scaling up target compound purification. This system features different column cell formats, allowing for higher loading capacity.

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CPC System Components


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